Opportunity Information: Apply for HRSA 20 046
The Regional Genetics Networks (RGN) funding opportunity (HRSA 20-046) is a Health Resources and Services Administration (HRSA) discretionary grant offered as a cooperative agreement through the U.S. Department of Health and Human Services. The program is designed to build and sustain a regional infrastructure that helps health care professionals better understand genetic disorders and improve how patients and families are identified, referred, and connected to appropriate genetic services. At its core, the opportunity focuses on strengthening coordinated systems of care so that people with genetic conditions, or those at risk, can receive timely follow-up, treatment coordination, and access to specialized genetics resources, with a strong emphasis on improving reach for underserved communities.
Funded networks are expected to create practical, working mechanisms for finding individuals and families who have, or may be at risk for, genetic disorders and then linking them to genetic services. This includes improving pathways for screening, referral, care coordination, and follow-up across a region, rather than operating in isolated pockets. A central priority is equity: applicants are expected to focus on populations that are underserved, meaning groups that face barriers such as geography, limited specialty availability, cost, insurance gaps, language barriers, or historically lower access to genetics expertise and follow-up care.
A major component of the work is coordination with two related HRSA initiatives. First, each RGN must align with the Advances in Integrating Genetics into Clinical Care (AIGCC) program (HRSA-20-050) to strengthen the education and training pipeline for health professionals. The intent is to raise clinical confidence and competence so that providers can better recognize potential genetic conditions, make appropriate referrals to genetics services, and apply genetic information in clinical management, especially when serving underserved populations. Second, networks must coordinate with the National Genetics Education and Family Support Program (HRSA-20-049) to expand education and support for families. This family-facing element is meant to improve understanding of genetics and available services, helping families navigate testing, counseling, and care options, again with particular attention to those who are underserved.
The notice also highlights expanding access through telehealth and telemedicine. RGNs are expected to help implement or scale remote service delivery approaches that reduce geographic and logistical barriers to genetic consultation, counseling, and follow-up. In practice, this means supporting systems that make it easier for patients and local clinicians to connect with genetic specialists when in-person access is limited, including rural and frontier areas where specialty genetics clinics may be sparse.
HRSA plans to fund one recipient per region, with a total of seven awards nationwide. Each award may be up to $600,000 (award ceiling), and recipients are responsible for supporting all states and territories listed in their assigned region, not just their home state. The seven regions are: New England (Connecticut, Maine, Massachusetts, New Hampshire, Rhode Island, Vermont); Mid-Atlantic (Delaware, District of Columbia, Maryland, New Jersey, New York, Pennsylvania, Puerto Rico, Virgin Islands, Virginia, West Virginia); Southeast (Alabama, Florida, Georgia, Louisiana, Mississippi, North Carolina, South Carolina, Tennessee); Midwest (Illinois, Indiana, Kentucky, Michigan, Minnesota, Ohio, Wisconsin); Heartland (Arkansas, Iowa, Kansas, Missouri, Nebraska, North Dakota, Oklahoma, South Dakota); Mountain (Arizona, Colorado, Montana, Nevada, New Mexico, Texas, Utah, Wyoming); and Western (Alaska, California, Guam, Hawaii, Idaho, Oregon, Washington). The opportunity was originally posted October 16, 2019, with an original closing date of January 14, 2020, and is listed under CFDA 93.110. Eligibility is described broadly as "Others" with additional eligibility details referenced in the full notice.
Overall, this opportunity is about building a coordinated regional backbone for genetics services: improving identification and referral pathways, training the broader health workforce to use genetic information appropriately, expanding telehealth-enabled access to genetics expertise, and ensuring families receive understandable education and support. The intended outcome is a more connected, equitable system where underserved patients and families are less likely to be missed, delayed, or disconnected from genetic evaluation and ongoing care.Apply for HRSA 20 046
- The Department of Health and Human Services, Health Resources and Services Administration in the health sector is offering a public funding opportunity titled "Regional Genetics Networks" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.110.
- This funding opportunity was created on Oct 16, 2019.
- Applicants must submit their applications by Jan 14, 2020. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $600,000.00 in funding.
- The number of recipients for this funding is limited to 7 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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Regional Genetics Networks (RGN) (HRSA 20-046) - Frequently Asked Questions
1) What is the Regional Genetics Networks (RGN) funding opportunity (HRSA 20-046)?
RGN (HRSA 20-046) is a Health Resources and Services Administration (HRSA) discretionary grant offered as a cooperative agreement through the U.S. Department of Health and Human Services. It supports building and sustaining a regional infrastructure to improve how genetic disorders are understood, identified, referred, and connected to appropriate genetic services.
2) What is the main purpose of the RGN program?
The core purpose is to strengthen coordinated systems of care across a region so that individuals with genetic conditions, or those at risk, receive timely follow-up, coordinated treatment support, and access to specialized genetics resources, with a strong emphasis on improving reach for underserved communities.
3) What kinds of activities are networks expected to carry out?
Funded networks are expected to create practical, working mechanisms for identifying individuals and families who have, or may be at risk for, genetic disorders and linking them to genetic services. This includes improving regional pathways for screening, referral, care coordination, and follow-up (rather than operating in isolated pockets).
4) What does the opportunity mean by building a "regional infrastructure"?
Based on the notice summary, "regional infrastructure" refers to coordinated, region-wide systems and processes that make it easier to identify patients at risk, route them into appropriate genetics services, and support ongoing follow-up and care coordination across the full region the award covers.
5) Is equity or serving underserved communities a required focus?
Yes. A central priority is equity. Applicants are expected to focus on underserved populations, meaning groups facing barriers such as geography, limited specialty availability, cost, insurance gaps, language barriers, or historically lower access to genetics expertise and follow-up care.
6) Who is considered "underserved" for purposes of this program?
The opportunity describes underserved populations as those facing barriers including geographic isolation, limited availability of specialty genetics services, cost barriers, insurance gaps, language barriers, or historically lower access to genetics expertise and follow-up care.
7) How does the program address gaps in provider knowledge about genetics?
Each RGN is expected to align with the Advances in Integrating Genetics into Clinical Care (AIGCC) program (HRSA-20-050). The intent is to strengthen education and training for health professionals so they can better recognize potential genetic conditions, make appropriate referrals, and apply genetic information in clinical management, especially for underserved populations.
8) What is the relationship between RGN and AIGCC (HRSA-20-050)?
RGNs must coordinate and align with AIGCC to strengthen the education and training pipeline for health professionals. This coordination is intended to improve clinician confidence and competence related to recognizing genetic conditions, referring patients, and using genetic information appropriately in care.
9) How does the program support patients and families directly?
Networks must coordinate with the National Genetics Education and Family Support Program (HRSA-20-049) to expand education and support for families. This family-facing component is meant to improve understanding of genetics and available services and help families navigate testing, counseling, and care options, with particular attention to underserved families.
10) What is the relationship between RGN and the National Genetics Education and Family Support Program (HRSA-20-049)?
RGNs are expected to coordinate with HRSA-20-049 to expand education and support for families, helping them better understand genetics, access services, and navigate care pathways.
11) Does this opportunity encourage telehealth or telemedicine for genetics services?
Yes. The notice highlights expanding access through telehealth and telemedicine. RGNs are expected to help implement or scale remote service delivery approaches that reduce geographic and logistical barriers to genetic consultation, counseling, and follow-up.
12) What is the practical goal of telehealth under this program?
The practical goal is to make it easier for patients and local clinicians to connect with genetic specialists when in-person access is limited, including in rural and frontier areas where specialty genetics clinics may be sparse.
13) How many awards does HRSA plan to make under RGN?
HRSA plans to fund one recipient per region, for a total of seven awards nationwide.
14) What is the maximum award amount?
Each award may be up to $600,000 (the award ceiling).
15) Do recipients only serve their home state?
No. Recipients are responsible for supporting all states and territories listed in their assigned region, not just their home state.
16) What are the seven RGN regions and which states and territories are in each?
The seven regions listed in the opportunity are:
- New England: Connecticut, Maine, Massachusetts, New Hampshire, Rhode Island, Vermont
- Mid-Atlantic: Delaware, District of Columbia, Maryland, New Jersey, New York, Pennsylvania, Puerto Rico, Virgin Islands, Virginia, West Virginia
- Southeast: Alabama, Florida, Georgia, Louisiana, Mississippi, North Carolina, South Carolina, Tennessee
- Midwest: Illinois, Indiana, Kentucky, Michigan, Minnesota, Ohio, Wisconsin
- Heartland: Arkansas, Iowa, Kansas, Missouri, Nebraska, North Dakota, Oklahoma, South Dakota
- Mountain: Arizona, Colorado, Montana, Nevada, New Mexico, Texas, Utah, Wyoming
- Western: Alaska, California, Guam, Hawaii, Idaho, Oregon, Washington
17) What does "one recipient per region" imply for applicants?
It implies that, within each region, HRSA intends to make a single award to one recipient that is responsible for region-wide coverage across all listed states and territories in that region.
18) What kind of grant mechanism is this?
This opportunity is described as a discretionary grant offered as a cooperative agreement.
19) When was the opportunity posted and when was it originally due?
The opportunity was originally posted on October 16, 2019, with an original closing date of January 14, 2020.
20) What is the CFDA number for this opportunity?
The opportunity is listed under CFDA 93.110.
21) Who is eligible to apply?
Eligibility is described broadly as "Others," with additional eligibility details referenced in the full notice.
22) What outcomes is this program trying to achieve?
The intended outcome is a more connected, equitable regional system where underserved patients and families are less likely to be missed, delayed, or disconnected from genetic evaluation and ongoing care. This is pursued through improved identification and referral pathways, better care coordination and follow-up, strengthened workforce training, telehealth expansion, and increased family education and support.
23) Is the focus on clinical care, education, or family support?
The opportunity combines all three: coordinated systems of care (clinical pathways and follow-up), alignment with AIGCC for health professional education and training, and coordination with the National Genetics Education and Family Support Program for family education and support.
24) Does the program focus on single sites or isolated projects?
No. The program emphasizes improving pathways and coordination across an entire region rather than operating in isolated pockets.
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