Opportunity Information: Apply for MP CPI 19 001

The OMH Hepatitis B Demonstration Grant Program (Funding Opportunity Number MP CPI 19 001) is a discretionary federal grant offered by the U.S. Department of Health and Human Services under the Office of the Assistant Secretary for Health, Office of Minority Health (OMH). Its central purpose is to support the creation and implementation of Hepatitis B "model programs" that can be replicated and scaled, with the long-term aim of ending hepatitis B virus (HBV) transmission across key routes (including perinatal transmission, transmission among children, and transmission among adults) while also reducing illness and deaths linked to chronic HBV infection. In practical terms, the program is designed to strengthen community-level systems that find people at risk, prevent new infections through vaccination, identify existing infections through testing, and ensure timely connection to medical care and ongoing monitoring for those who test positive.

A major emphasis of the opportunity is improving the delivery of prompt, responsive, and efficient HBV-related services for populations that are often missed by routine prevention and healthcare pathways. The target groups explicitly highlighted include people born in countries where HBV is endemic, as well as U.S.-born individuals who were not vaccinated as infants and whose parents were born in countries with very high HBV prevalence. The program also prioritizes reaching household contacts and sexual partners of people living with HBV infection, recognizing that these groups face elevated risk and benefit from rapid vaccination and/or testing. Another core focus is infants, children, and adolescents who might "slip through the cracks," which points to gaps in screening, immunization completion, perinatal follow-up, school or adolescent vaccine catch-up, and transitions between pediatric and adult care. Overall, the grant is oriented toward improving the reach and reliability of the essential services needed to eliminate hepatitis B, especially in communities where barriers such as language access, limited health coverage, immigration-related concerns, stigma, and fragmented care systems can reduce uptake of prevention and treatment.

OMH frames the approach around building collaborative partnerships rather than funding isolated, stand-alone projects. Applicants are expected to form and operate partnerships that can build capacity to scale up HBV vaccination, expand testing, strengthen linkage to care, and enhance surveillance and data use. The surveillance component matters because elimination efforts depend on knowing who is being reached, where transmission risks persist, and whether vaccination, testing, and care connections are happening quickly and consistently. The opportunity also aligns with national hepatitis B elimination goals recommended by the National Academies of Sciences (NAS), signaling that funded work should support broader national strategies and measurable progress toward elimination benchmarks. In addition, OMH indicates that successful applicants and their partnerships are expected to implement community-level strategies outlined in the full announcement, which implies that the program is structured around a defined set of interventions rather than open-ended innovation alone.

In terms of funding structure and scale, the grant lists an award ceiling of $500,000 and anticipates making about 7 awards. The funding activity category is Health, and it is associated with CFDA number 93.137. The opportunity was created on February 13, 2019, with an original closing date of April 13, 2019. While the announcement text emphasizes service delivery and community implementation, the "demonstration" nature of the program suggests an expectation that grantees will not only provide services but also show how integrated models and partnerships can be implemented effectively, generate actionable lessons, and position programs for broader replication and scale-up.

Eligibility is broad across public and private sectors that commonly run public health and community health initiatives. Eligible applicants include state governments, county governments, and special district governments; public and state-controlled institutions of higher education; private institutions of higher education; public housing authorities and Indian housing authorities; Native American tribal organizations (other than federally recognized tribal governments); and nonprofit organizations both with and without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories). This wide eligibility reflects the program's intent to build community-rooted collaborations that can operate across clinical settings, public health agencies, schools and universities, housing-linked services, and nonprofit networks serving immigrant and minority communities.

Taken together, the OMH Hepatitis B Demonstration Grant Program is best understood as a targeted investment in community-driven, partnership-based public health models that combine prevention (vaccination), identification (testing), connection to medical management (linkage to care), and improved tracking (surveillance). The end goal is to close persistent service gaps affecting high-risk and underserved populations and to accelerate progress toward national hepatitis B elimination by demonstrating scalable, locally effective strategies that reduce new infections and lessen the health burden of chronic HBV.

  • The Department of Health and Human Services, Office of the Assistant Secretary for Health in the health sector is offering a public funding opportunity titled "OMH Hepatitis B Demonstration Grant Program" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.137.
  • This funding opportunity was created on Feb 13, 2019.
  • Applicants must submit their applications by Apr 13, 2019 No Explanation. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $500,000.00 in funding.
  • The number of recipients for this funding is limited to 7 candidate(s).
  • Eligible applicants include: State governments, County governments, Special district governments, Public and State controlled institutions of higher education, Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education.
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