Opportunity Information: Apply for PAR 24 320
The NCI Continuing Umbrella of Research Experiences (CURE) Mentored Clinical Scientist Research Career Development Award (K08 Clinical Trial Not Allowed) is an NIH grant opportunity from the National Cancer Institute designed to help early-career clinicians build the skills, track record, and independence needed for a long-term research career in cancer. Its central goal is career development: it provides salary support and protected time so that a clinician with a clinical doctoral degree can pursue an intensive, supervised (mentored) research and training experience. The program supports research in biomedical and behavioral science, including translational cancer research, and it is structured to move the awardee toward research independence and future competition for major NIH research grants such as the R03, R21, or R01.
A defining feature of this NCI-sponsored K08 is its focus on strengthening the cancer research workforce by supporting clinical scientists from backgrounds that have been shown to be nationally underrepresented in health-related science. The opportunity is aimed at candidates who are committed to a career in basic biomedical, behavioral, or translational cancer research, including work that addresses cancer health disparities. In practice, the expectation is that the mentored period will help the scholar deepen scientific expertise, develop strong research productivity, and assemble the preliminary data, publications, and grant-writing experience needed to successfully transition to independent funding.
This specific funding announcement is identified as PAR-24-320, offered as a discretionary grant in the Education and Health activity area (CFDA 93.398). While the award supports research career development, it explicitly does not allow clinical trials under this mechanism, meaning the proposed K08 research and training plan must fit within non-clinical-trial parameters as defined by NIH policy. The opportunity was created on 2024-12-02, and the original closing date listed is 2027-11-12.
Eligible applicant organizations span a wide range of U.S.-based entities, reflecting the fact that the award is made to an institution on behalf of the candidate. Eligible applicants include public and private institutions of higher education, independent school districts, state, county, city or township governments, special district governments, federally recognized Native American tribal governments, and Native American tribal organizations other than federally recognized tribal governments. Eligibility also includes public housing authorities/Indian housing authorities, nonprofits with and without 501(c)(3) status (other than institutions of higher education), for-profit organizations other than small businesses, small businesses, and other types of organizations. The announcement also highlights additional eligible applicant types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations, eligible federal agencies, regional organizations, Indian/Native American tribal governments that are not federally recognized, and U.S. territories or possessions.
Foreign involvement is tightly restricted. Non-domestic (non-U.S.) entities are not eligible to apply, non-domestic components of U.S. organizations are not eligible to apply, and foreign components (as defined by the NIH Grants Policy Statement) are not allowed. In short, the program is meant to build U.S.-based mentored career development capacity in cancer research while expanding participation among groups that have been historically underrepresented in the health research enterprise.Apply for PAR 24 320
- The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "NCI Continuing Umbrella of Research Experiences (CURE) Mentored Clinical Scientist Research Career Development Award (K08 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.398.
- This funding opportunity was created on 2024-12-02.
- Applicants must submit their applications by 2027-11-12.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs): NCI CURE Mentored Clinical Scientist Research Career Development Award (K08, Clinical Trial Not Allowed) - PAR-24-320
1) What is this funding opportunity?
This opportunity is the NCI Continuing Umbrella of Research Experiences (CURE) Mentored Clinical Scientist Research Career Development Award (K08 Clinical Trial Not Allowed). It is an NIH grant opportunity from the National Cancer Institute (NCI) designed to support early-career clinicians as they build the skills, research record, and trajectory needed for a long-term, independent cancer research career.
2) What is the main purpose of the NCI CURE K08?
The central purpose is career development. The award provides salary support and protected time so a clinician with a clinical doctoral degree can complete an intensive, supervised (mentored) research and training experience. The structure is intended to move the awardee toward research independence and future competition for larger NIH research grants (for example, R03, R21, or R01).
3) What kind of research areas does this K08 support?
The program supports research in biomedical and behavioral science, including translational cancer research. It also includes work that addresses cancer health disparities, consistent with the program's stated emphasis on strengthening and diversifying the cancer research workforce.
4) Who is this award designed to support?
This NCI-sponsored K08 is aimed at early-career clinicians who are committed to a career in basic biomedical, behavioral, or translational cancer research. A defining feature is its focus on supporting clinical scientists from backgrounds that have been shown to be nationally underrepresented in health-related science.
5) What does "mentored" mean in this program?
The award supports an intensive, supervised research and training experience. The expectation is that during the mentored period, the scholar will deepen scientific expertise, build research productivity, and develop the publications, preliminary data, and grant-writing experience needed to transition to independent research funding.
6) Is the award intended to lead to future NIH funding?
Yes. The opportunity is structured to move the awardee toward research independence and to strengthen competitiveness for major NIH research grants, specifically noting examples such as the R03, R21, or R01.
7) Are clinical trials allowed under this K08?
No. This funding announcement explicitly states "Clinical Trial Not Allowed." The proposed K08 research and training plan must fit within non-clinical-trial parameters as defined by NIH policy.
8) What is the funding announcement number for this opportunity?
The funding announcement is identified as PAR-24-320.
9) Which federal agency is offering this grant?
The opportunity is offered through the National Institutes of Health (NIH), specifically the National Cancer Institute (NCI).
10) What type of grant is this categorized as?
It is described as a discretionary grant in the Education and Health activity area.
11) What is the CFDA number associated with this opportunity?
The opportunity is listed under CFDA 93.398.
12) When was this opportunity created and what is the closing date listed?
The opportunity was created on 2024-12-02. The original closing date listed is 2027-11-12.
13) Who applies for the award: the individual or the organization?
The award is made to an institution on behalf of the candidate. In other words, the applicant organization submits the application to support the clinician candidate's mentored career development program.
14) What types of U.S. organizations are eligible to apply?
Eligible applicants span a wide range of U.S.-based entities, including:
- Public and private institutions of higher education
- Independent school districts
- State, county, city, or township governments
- Special district governments
- Federally recognized Native American tribal governments
- Native American tribal organizations (other than federally recognized tribal governments)
- Public housing authorities/Indian housing authorities
- Nonprofits with and without 501(c)(3) status (other than institutions of higher education)
- For-profit organizations other than small businesses
- Small businesses
- Other types of organizations
15) Are minority-serving institutions specifically included as eligible applicants?
Yes. The announcement highlights additional eligible applicant types, including:
- Historically Black Colleges and Universities (HBCUs)
- Hispanic-serving institutions
- Tribally Controlled Colleges and Universities (TCCUs)
- Alaska Native and Native Hawaiian Serving Institutions
- Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)
16) Are faith-based or community-based organizations eligible to apply?
Yes. The eligible applicant list includes faith-based or community-based organizations.
17) Are federal agencies eligible to apply?
Yes. The announcement lists eligible federal agencies among eligible applicant types.
18) Are U.S. territories or possessions eligible to apply?
Yes. The eligible applicant types include U.S. territories or possessions.
19) Can non-U.S. (foreign) organizations apply?
No. Non-domestic (non-U.S.) entities are not eligible to apply.
20) Can a U.S. organization apply if the work will be performed at a non-U.S. component?
No. Non-domestic components of U.S. organizations are not eligible to apply.
21) Are foreign components allowed in any form?
No. Foreign components (as defined by the NIH Grants Policy Statement) are not allowed.
22) Why does this program emphasize underrepresented backgrounds in health-related science?
A defining feature of this NCI-sponsored K08 is its goal of strengthening the cancer research workforce by supporting clinical scientists from backgrounds that have been shown to be nationally underrepresented in health-related science, while building U.S.-based mentored career development capacity in cancer research.
23) Is the program relevant to researchers focused on cancer health disparities?
Yes. The opportunity explicitly includes translational cancer research and notes that it includes work addressing cancer health disparities.
24) What outcomes are expected from the mentored period?
The description emphasizes outcomes that position the scholar for independence, including deeper scientific expertise, strong research productivity, preliminary data, publications, and experience with grant writing to support a transition to independent funding.
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