Opportunity Information: Apply for PAR 24 320

The NCI Continuing Umbrella of Research Experiences (CURE) Mentored Clinical Scientist Research Career Development Award (K08 Clinical Trial Not Allowed) is an NIH grant opportunity from the National Cancer Institute designed to help early-career clinicians build the skills, track record, and independence needed for a long-term research career in cancer. Its central goal is career development: it provides salary support and protected time so that a clinician with a clinical doctoral degree can pursue an intensive, supervised (mentored) research and training experience. The program supports research in biomedical and behavioral science, including translational cancer research, and it is structured to move the awardee toward research independence and future competition for major NIH research grants such as the R03, R21, or R01.

A defining feature of this NCI-sponsored K08 is its focus on strengthening the cancer research workforce by supporting clinical scientists from backgrounds that have been shown to be nationally underrepresented in health-related science. The opportunity is aimed at candidates who are committed to a career in basic biomedical, behavioral, or translational cancer research, including work that addresses cancer health disparities. In practice, the expectation is that the mentored period will help the scholar deepen scientific expertise, develop strong research productivity, and assemble the preliminary data, publications, and grant-writing experience needed to successfully transition to independent funding.

This specific funding announcement is identified as PAR-24-320, offered as a discretionary grant in the Education and Health activity area (CFDA 93.398). While the award supports research career development, it explicitly does not allow clinical trials under this mechanism, meaning the proposed K08 research and training plan must fit within non-clinical-trial parameters as defined by NIH policy. The opportunity was created on 2024-12-02, and the original closing date listed is 2027-11-12.

Eligible applicant organizations span a wide range of U.S.-based entities, reflecting the fact that the award is made to an institution on behalf of the candidate. Eligible applicants include public and private institutions of higher education, independent school districts, state, county, city or township governments, special district governments, federally recognized Native American tribal governments, and Native American tribal organizations other than federally recognized tribal governments. Eligibility also includes public housing authorities/Indian housing authorities, nonprofits with and without 501(c)(3) status (other than institutions of higher education), for-profit organizations other than small businesses, small businesses, and other types of organizations. The announcement also highlights additional eligible applicant types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations, eligible federal agencies, regional organizations, Indian/Native American tribal governments that are not federally recognized, and U.S. territories or possessions.

Foreign involvement is tightly restricted. Non-domestic (non-U.S.) entities are not eligible to apply, non-domestic components of U.S. organizations are not eligible to apply, and foreign components (as defined by the NIH Grants Policy Statement) are not allowed. In short, the program is meant to build U.S.-based mentored career development capacity in cancer research while expanding participation among groups that have been historically underrepresented in the health research enterprise.

  • The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "NCI Continuing Umbrella of Research Experiences (CURE) Mentored Clinical Scientist Research Career Development Award (K08 Clinical Trial Not Allowed)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.398.
  • This funding opportunity was created on 2024-12-02.
  • Applicants must submit their applications by 2027-11-12.
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
Apply for PAR 24 320

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